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Partial purification of protease-solubilised low Km cyclic nucleotide phosphodiesterase from liver

✍ Scribed by Glenn N. Major; Ernest G. Loten; John G.T. Sneyd


Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
721 KB
Volume
15
Category
Article
ISSN
0020-711X

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Partial purification and characterizatio
✍ HΓ₯kan Bergstrand; Britta Lundquist πŸ“‚ Article πŸ“… 1978 πŸ› Springer 🌐 English βš– 460 KB

DEAE-Sephadex chromatography reveals the presence in extracts of human bronchial tissue of at least three separate cyclic nucleotide phosphodiesterases: a cyclic GMP-specific high affinity enzyme, a non-specific low affinity enzyme, and a high affinity cyclic AMP-specific enzyme. The activity of eac