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Partial purification of endogenous hepatic (+)-[3H] SKF 10047 binding to sigma opioid receptors

โœ Scribed by L. V. Nagornaya; N. N. Samovilova; N. V. Korobov; V. A. Vinogradov


Publisher
Springer US
Year
1988
Tongue
English
Weight
367 KB
Volume
106
Category
Article
ISSN
0007-4888

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โœ Li-i Tsao; Tsung-Ping Su ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 111 KB

A naloxone-sensitive, haloperidol-sensitive, [ 3 H](1)SKF-10047-binding protein was partially purified from rat liver and rat brain membranes in an affinity chromatography originally designed to purify sigma receptors. Detergent-solubilized extracts from membranes were adsorbed to Sephadex G-25 resi