An extract of bovine hypothalamus is known to be mitogenic for human keratinocytes in vitro. In order to identify the responsible substance(s), biochemical characterization and subsequent bioassay of the extract in a serum-free culture system were performed. The keratinocyte growth-promoting activit
Partial purification of a low-molecular-weight growth factor from chicken brain
β Scribed by Robert L. Carlone; Michel P. Rathbone
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 841 KB
- Volume
- 124
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Previously, we reported that mouse tumors contain a low molecular weight factor which is capable of affecting __in vitro__ properties of macrophages. We now describe the purification to homogeneity of the only factor with macrophage modulating activity from one of these tumors, Lewis lu
## Abstract A dialysable lowβmolecularβweight factor capable of affecting __in vitro__ properties of macrophages was extracted from four different mouse tumors. This factor not only modulates closely related properties of peritoneal macrophages such as spreading and migration but also inhibits lipo