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Partial purification of a bone-resorbing factor elaborated from human allogeneic cultures

✍ Scribed by John E. Horton; William J. Koopman; John J. Farrar; Janet Fuller-Bonar; Stephen E. Mergenhagen


Book ID
115811681
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
831 KB
Volume
43
Category
Article
ISSN
0008-8749

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Partial purification and characterizatio
✍ DignaοΏ½, A. ;Holldorf, A. W. πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 565 KB

A growth factor capable of stimulating DNA synthesis of Balb/c 3T3 cells was purified by heparin-Sepharose column chromatography about 1900-fold from the cytosol of human prostatic tissues obtained at autopsy or open prostatectomy. This growth factor bound to heparin-Sepharose in the presence of 0.5