## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Partial purification and characterization of a tumor necrosis factor-α converting activity
✍ Scribed by Sylvie Robache-Gallea; Jean-Michel Bruneau; Hugue Robbe; Valérie Morand; CÉCile Capdevila; Neerja Bhatnagar; Salem Chouaib; Sergio Roman-Roman
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 991 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0014-2980
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Tumor necrosis factor alpha-converting enzyme (TACE, also known as ADAM17) was recently involved in the pathogenesis of insulin resistance. We observed that TACE activity was significantly higher in livers of mice fed a high-fat diet (HFD) for 1 month, and this activity was increased in liver > whit
Purification of cytokines was carried out while monitoring their in vivo anti-tumor activity and in vitro cytotoxic activities. As a result, purified new cytokines were obtained from culture supernatant of a histiocytic cell line and from rabbit serum. Briefly, a new cytokine (HSF, histiocyte-secret