Partial laryngectomy as salvage surgery for radiation failures in T1–T2 laryngeal cancer

✍ Scribed by Sergio Rodríguez-Cuevas; Sonia Labastida; Domingo Gonzalez; Nicolas Briseño; Hector Cortes

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 59 KB
• Volume: 20
• Category: Article
• ISSN: 1043-3074
• DOI: 10.1002/(sici)1097-0347(199810)20:7<630::aid-hed9>3.0.co;2-k

✦ Synopsis

Background:

Radiotherapy is the treatment of choice for early glottic carcinoma. thirteen percent to 24% of patients require salvage surgery. to evaluate time of recurrence, site, and locoregional control, we retrospectively reviewed 29 patients treated from 1981 to 1996.

Methods:

There were 28 men and 1 woman. mean age was 63 years. twenty were t1 (69%) and 9 were t2 (31%). median time of recurrence was 14.5 months. in 14 patients (52%), a partial laryngectomy was done, and 13 patients had a total laryngectomy. two refused surgery.

Results:

One patient relapsed after salvage surgery. five-year survival after salvage surgery was 92%, with no difference between partial and total laryngectomy (p = 0.2).

Conclusions:

Recurrences after failure to radiotherapy in t1-t2 glottic carcinoma could be salvaged with partial laryngectomy in 52% of patients, preserving laryngeal function, with adequate tumor control and acceptable morbidity. the selection of the surgical procedure is based on the tumor extension.