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Partial differential equations of chemotaxis and angiogenesis

✍ Scribed by B. D. Sleeman; H. A. Levine


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
166 KB
Volume
24
Category
Article
ISSN
0170-4214

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✦ Synopsis


Abstract

The topic of this paper is concerned with an investigation of the qualitative properties of solutions to the following problem.

Let Ξ©βŠ‚R^n^ be a bounded domain with boundary βˆ‚Ξ©.

We seek solutions P,Ο‰βˆˆR^m+1^ of the system
subject to the β€˜no‐flux’ boundary condition
where n denotes the inward pointing normal to βˆ‚Ξ©. To close the system we prescribe the initial conditions
In this system D is a constant diffusion coefficient, P is a population density and Ο‰ is a vector of nutrients or chemicals whose dynamics influences the movement of P.

Notice here that the substances Ο‰ do not diffuse. If they do then the second equation of (1) is modified to

where d is a positive semi‐definite diagonal matrix. This more general system includes the so‐called Keller–Segel model of Biology ([1] Keller EF, Segel LA. Initiation of slime mold aggregation viewed as an instability. Journal of Theoretical Biology 1970; 26: 339–415). To motivate our study of system (1)–(3) we begin by outlining two themes. One basic to developmental biology and the other from angiogenesis. Copyright Β© 2001 John Wiley & Sons, Ltd.


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