Partial deletion of the X chromosome in gonadal dysgenesis 46,X,del(X)(p22) identified by BUdR treatment

✍ Scribed by P. Petrinelli; A. Antonelli; P. Gabellini; F. Gigliani; L. Marcucci; B. Nicoletti

• Publisher: Springer
• Year: 1978
• Tongue: English
• Weight: 336 KB
• Volume: 45
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00278734

✦ Synopsis

In this report we describe a deletion of the short arm of the X chromosome in a 16-year-old female with gonadal dysgenesis. The breakpoint was localized by BUdR treatment and acridine orange staining in region 2, band 2. Of the examined cells, 3% showed an early replication of the deleted X chromosome.