Partial deficiency of eosinophil peroxidase
โ Scribed by Hoffmann, J. J. M. L. ;Tielens, A. G. W. M.
- Publisher
- Springer-Verlag
- Year
- 1987
- Weight
- 219 KB
- Volume
- 54
- Category
- Article
- ISSN
- 1432-0584
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๐ SIMILAR VOLUMES
Hereditary eosinophil peroxidase (EPO; EC 1.11.1.7) deficiency is a rare abnormality without clinical symptoms characterized by decreased or absent peroxidase activity and decreased volume of the granule matrix in eosinophils. Nearly 100 cases have been reported, but a specific mutation has been rep
Increased numbers of eosinophils and increased concentrations of plasma proteins have been found in the airways of patients with mild asthma. We used an intact guinea pig trachea model to investigate the role of eosinophil peroxidase (EPO) in altering the function of the airway epithelial barrier. E