✦ LIBER ✦
Partial characterisation of an elastase-like enzyme secreted by human and monkey alveolar macrophages
✍ Scribed by Hubert De Cremoux; William Hornebeck; Marie-Claude Jaurand; Jean Bignon; Ladislas Robert
- Book ID
- 104505049
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 536 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0022-3417
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✦ Synopsis
An elastinolytic activity on soluble and insoluble elastin has been demonstrated in the culture medium of human and monkey alveolar macrophages. This activity is potentiated by latex particles in the medium. An enzyme resembling some other elastases was partially purified and characterised. It differs from other elastases in its affinity for elastin and a synthetic substrate, its susceptibility to various kinds of inhibitors and by its metal ion requirement.