𝔖 Bobbio Scriptorium
✦   LIBER   ✦

[Part 1: Biological Sciences] || Interferon Enhancement of the Invasive Capacity of Ewing Sarcoma Cells in vitro

✍ Scribed by Gene P. Siegal, Unnur P. Thorgeirsson, Raimondo G. Russo, Donald M. Wallace, Lance A. Liotta and Shelby L. Berger

Book ID
123623701
Publisher
National Academy of Sciences
Year
1982
Tongue
English
Weight
896 KB
Volume
79
Category
Article
ISSN
0027-8424

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Targeting of EWS/FLI-1 by RNA interferen
Targeting of EWS/FLI-1 by RNA interference attenuates the tumor phenotype of Ewing's sarcoma cells in vitro
✍ Howard A Chansky; Fariba Barahmand-pour; Qi Mei; Waqqar Kahn-Farooqi; Anna Zieli πŸ“‚ Article πŸ“… 2004 πŸ› Elsevier Science 🌐 English βš– 881 KB

## Abstract The defining cytogenetic abnormality of Ewing's sarcoma is the presence of a balanced t(11;22) translocation expressing the EWS/FLI‐1 chimeric fusion protein. The effect of EWS/FLI‐1 appears to be dominant negative since over‐expression of EWS does not overcome the sarcoma phenotype. Pr