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PARP-1 regulates the expression of caspase-11

✍ Scribed by Lang Yoo; Seokheon Hong; Ki Soon Shin; Shin Jung Kang

Book ID
116301706
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
454 KB
Volume
408
Category
Article
ISSN
0006-291X

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## Abstract Repression of E‐cadherin expression by the transcription factor, Snail, is implicated in epithelial to mesenchymal transition and cancer progression. We show here that Integrin‐Linked Kinase (ILK) regulates E‐cadherin expression through Poly(ADP‐ribose) polymerase‐1 (PARP‐1). ILK overex