Paroxysms of excitement: sodium channel dysfunction in heart and brain

Solution structure of the cytoplasmic li

Solution structure of the cytoplasmic linker between domain III-S6 and domain IV-S1 (III–IV linker) of the rat brain sodium channel in SDS micelles

✍ Kazuhide Miyamoto; Terumichi Nakagawa; Yoshihiro Kuroda 📂 Article 📅 2001 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 495 KB

The solution structure of the 36-mer peptide MP-5A in SDS micelles was investigated by CD and 1 H-NMR spectroscopies. The MP-5A was dissected from the cytoplasmic linker (K1482-A1517) connecting domain III-segment 6 (IIIS6) and domain IV-segment 1 (IVS1; III-IV linker) of the rat brain type IIA sodi