Parkinsonism associated with acute intracranial hematomas: An [18F]dopa positron-emission tomography study
β Scribed by Dr. Nora Turjanski; Brian Pentland; Andrew J. Lees; David J. Brooks
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 586 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
β¦ Synopsis
We present the case of a 36-year-old woman with a right temporal hematoma and an overlying subdural hematoma following rupture of a right middle cerebral artery aneurysm. Three weeks after recovering consciousness, she developed a levodopa-responsive parkinsonian syndrome involving the right limbs. A year after the vascular event, she reported subjective improvement in her parkinsonism, which has remained stable since. 18F-dopa positron-emission tomography showed a marked reduction of uptake in the left putamen, raising the possibility that the intracranial hemorrhage unmasked latent Parkinson's disease. To the best of our knowledge, this is the first case of parkinsonism associated with spontaneous acute intracerebral and subdural hematomas.
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There is increasing evidence for familial aggregation in Parkinson's disease (PD). It is possible that some asymptomatic relatives of I'D patients have subclinical nigral Lewy body pathology and their identification could help determine the true prevalence of the disease. We used 18F-dopa positron e