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Parkinsonism associated with acute intracranial hematomas: An [18F]dopa positron-emission tomography study

✍ Scribed by Dr. Nora Turjanski; Brian Pentland; Andrew J. Lees; David J. Brooks


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
586 KB
Volume
12
Category
Article
ISSN
0885-3185

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✦ Synopsis


We present the case of a 36-year-old woman with a right temporal hematoma and an overlying subdural hematoma following rupture of a right middle cerebral artery aneurysm. Three weeks after recovering consciousness, she developed a levodopa-responsive parkinsonian syndrome involving the right limbs. A year after the vascular event, she reported subjective improvement in her parkinsonism, which has remained stable since. 18F-dopa positron-emission tomography showed a marked reduction of uptake in the left putamen, raising the possibility that the intracranial hemorrhage unmasked latent Parkinson's disease. To the best of our knowledge, this is the first case of parkinsonism associated with spontaneous acute intracerebral and subdural hematomas.


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✍ Dr P. Piccini; P. K. Morrish; N. Turjanski; G. V. Sawle; D. J. Burn; R. A. Weeks πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 790 KB

There is increasing evidence for familial aggregation in Parkinson's disease (PD). It is possible that some asymptomatic relatives of I'D patients have subclinical nigral Lewy body pathology and their identification could help determine the true prevalence of the disease. We used 18F-dopa positron e