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Parham-type cyclization and nucleophilic addition - N-acyliminium ion cyclization sequences for the construction of the isoquinoline nucleus

✍ Scribed by M.Isabel Collado; Nuria Sotomayor; María-Jesús Villa; Esther Lete


Book ID
103413043
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
253 KB
Volume
37
Category
Article
ISSN
0040-4039

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## Abstract An efficient methodology for the synthesis of isoindolo[1,2‐__a__]isoquinolones based on two Parham‐type cyclizations allowing the formation of the five‐ and six‐membered nitrogenated rings from carbamate or diacylamine precursors is described. The synthetic potential of this method has