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Parental epigenetic control of embryogenesis: a balance between inheritance and reprogramming?

✍ Scribed by Mark E Gill; Serap Erkek; Antoine HFM Peters

Book ID
113525302
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
518 KB
Volume
24
Category
Article
ISSN
0955-0674

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## Abstract Summary: Genome‐wide epigenetic reprogramming by demethylation occurs in early mouse embryos and primordial germ cells. In early embryos many single‐copy sequences become demethylated both by active and passive demethylation, whereas imprinted gene methylation remains unaffected. In pri