Parental consanguineous marriages and age at onset of schizophrenia
β Scribed by Samane Nafissi; Maryam Ansari-Lari; Mostafa Saadat
- Book ID
- 119365739
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 150 KB
- Volume
- 126
- Category
- Article
- ISSN
- 0920-9964
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π SIMILAR VOLUMES
The existence of a rare autosomal gene which in the homozygous state would cause mitotic nondisjunction in the Down zygote has been hypothesized in the past by Alfi et al. (1980). This hypothesis can be supported or contradicted by the study of the frequency of consanguineous marriages among parents
## Abstract A number of studies support a possible link between mitochondrial dysfunction and schizophrenia. To test the hypothesis of a direct contribution of mitochondrial DNA (mtβDNA) in susceptibility to DSMβIVβTRβschizophrenia, we looked for differences in the frequency distribution of the maj