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Parental age and the origin of trisomy 21

✍ Scribed by F. Dagna Bricarelli; M. Pierluigi; M. Landucci; A. Arslanian; D. A. Coviello; M. A. Ferro; P. Strigini


Publisher
Springer
Year
1989
Tongue
English
Weight
754 KB
Volume
82
Category
Article
ISSN
0340-6717

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πŸ“œ SIMILAR VOLUMES


Origin of nondisjunction in trisomy 21 s
✍ Juberg, Richard C. ;Mowrey, Philip N. πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 English βš– 379 KB πŸ‘ 2 views

The Q-band polymorphism of chromosome 21 permits assignment of the origin of meiotic nondisjunction by parent and meiotic division in a certain proportion of cases. We have compiled all reports through 1982 (including earlier studies using structural abnormality) and have shown that maternal origin

Grandmaternal age at birth of parents of
✍ Z. Papp; Γ‰. VΓ‘radi; Z. SzabΓ³ πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 211 KB

The authors investigated the age of the parents and grandmothers of 262 children with simple trisomy 21. In cases in which the mother was under 30, the mean grandmaternal age was higher than that of the controls. This might mean that some of these cases, being the children of old mothers, began thei

Trisomy 21: Origin of non-disjunction
✍ J. Mazo; Amalia PΓ©rez Castillo; J. A. Abrisqueta πŸ“‚ Article πŸ“… 1982 πŸ› Springer 🌐 English βš– 379 KB

The Q-band heteromorphisms of chromosome 21 were used in a sample of 48 families with a Down's syndrome child to evaluate the origin of non-disjunction. The parental origin and the meiotic error were determined in 27 families, and in eight families only partial information was obtained. Paternal and

Origin of the extra chromosome in trisom
✍ J. F. Mattei; M. G. Mattei; S. Ayme; F. Giraud πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 230 KB

Of 61 families of children with trisomy 21, polymorphism of chromosome 21 elucidating the origin of the extra chromosome was found in 42. Nondisjunction was of paternal origin in 8 cases (19.04%) and the anomaly occurred with equal frequency during the first and second meiotic divisions. Maternal no