Parathyroid hormone (PTH) receptors and the biological response to PTH in osteoblasts have been shown to be influenced by glucocorticoids, growth factors, cytokines or PTH itself. Furthermore, components of extracellular matrix (ECM) appear to regulate the response to PTH as well. We investigated th
✦ LIBER ✦
Parathyroid hormone-related protein regulates osteoclast inhibitory lectin expression via multiple signaling pathways in osteoblast-like cells
✍ Scribed by Fang Zheng; Hui Liang; Rui Liu; Jin-Xing Quan; Xiao-Xia Li; Chen-Lin Dai; Gang Guo; Jing-Yu Zhang; Bao-Li Wang
- Book ID
- 107571222
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 453 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0969-711X
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## Abstract Inhibition of osteoblast‐mediated mineralization is one of the major catabolic effects of parathyroid hormone (PTH) on bone. Previously, we showed that PTH induces matrix γ‐carboxyglutamic acid (Gla) protein (MGP) expression and established that this induction is critical for PTH‐mediat