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Parathyroid hormone-related protein production and receptor expression by normal and malignant keratinocytes in vitro

✍ Scribed by Werkmeister, JR; Merryman, JI; Rosol, TJ; McCauley, LK; Capen, CC

Book ID
121908994
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
181 KB
Volume
17
Category
Article
ISSN
0169-6009

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Parathyroid hormone-related protein (PTHrP) is the cause of humoral hypercalcaemia of malignancy and interacts with parathyroid hormone (PTH) receptors. Breast cancer cells produce PTHrP in vitro and in vivo. The breast cancer cell line MCF-7, which products PTHrP and expresses PTHrP receptors, prol