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Parathyroid hormone-related protein: Primary osteolytic factor produced by breast tumor cells in vitro?

✍ Scribed by Arnold Tabuenca; Subburaman Mohan; Carlos A. Garberoglio; Patrick I. Borgen; Thomas Rosol; Thomas A. Linkhart


Publisher
Springer
Year
1995
Tongue
English
Weight
748 KB
Volume
19
Category
Article
ISSN
0364-2313

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## Abstract To attain full biological activity, the precursor pro‐parathyroid hormone‐related peptide (ProPTHRP) must be converted to the mature peptide PTHRP. We have examined the effect of inhibiting expression of the pro‐hormone convertase furin in H‐500 rat Leydig tumor cells on PTHRP productio