## Background: Parathyroid hormone-related protein (pthrp) is the primary factor responsible for humoral hypercalcemia of malignancy. the hypercalcemic actions of pthrp occur via stimulation of renal distal tubular calcium reabsorption and increased osteoclastic bone resorption. these effects of pt
Parathyroid hormone-related protein is expressed by prostatic neuroendocrine cells
โ Scribed by Masatsugu Iwamura; P.Anthony di Sant'agnese; Guan Wu; Abraham T.K. Cockett; Per-Anders Abrahamsson; Leonard J. Deftos
- Book ID
- 119047524
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 893 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0090-4295
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## Background: The importance of the expression of granin a (grn-a, chromogranin-a), calcitonin (ct) gene products (cgps), and parathyroid hormone-related protein (pthrp) has become appreciated in the neuroendocrine (ne) differentiation of prostate cancer. we have studied the prostate expression of
Parathyroid hormone-related protein (PTHrP) has previously been shown to be expressed in human prostatic tissue and in prostatic cancer cell lines. In the present study, PTHrP immunoreactivity was detected in the glandular epithelium of normal prostate and benign prostatic hyperplasia (BPH), as well