Parathyroid hormone (PTH) receptors and the biological response to PTH in osteoblasts have been shown to be influenced by glucocorticoids, growth factors, cytokines or PTH itself. Furthermore, components of extracellular matrix (ECM) appear to regulate the response to PTH as well. We investigated th
✦ LIBER ✦
Parathyroid Hormone-Related Protein (1–37) Induces cAMP Response in Human Osteoblast-Like Cells
✍ Scribed by J. A. Tsai; E. Bucht; A. Stark; U. Sjöstedt; O. Törring
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 317 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1432-0827
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## Abstract Parathyroid hormone (PTH), an anabolic agent for bone metabolism, has profound effects on gene expression in the osteoblast. Recently, we identified that amphiregulin (AR), an EGF‐like ligand, is an immediate early gene for PTH treatment and has an important role in bone metabolism. In