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Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: Role of the calcium-calcineurin-NFAT pathway

✍ Scribed by Hechang Huang; Daichi Chikazu; Olga S Voznesensky; Harvey R Herschman; Barbara E Kream; Hicham Drissi; Carol C Pilbeam

Book ID
111485876
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
361 KB
Volume
25
Category
Article
ISSN
0884-0431

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## Abstract Parathyroid hormone (PTH) exerts an anabolic action on bone but the mechanisms are incompletely understood. We showed previously that PTH interacts with the canonical Wnt‐β‐catenin signaling pathway via the transforming growth factor (TGF)‐β signaling molecule, Smad3, to modulate osteob