Human parathyroid hormone as a secretory
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Erik Rokkones; Sigurd H. Fromm; B. Najma Kareem; Helge Klungland; Ole K. Olstad;
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Article
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1995
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John Wiley and Sons
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English
β 910 KB
In a transgenic mouse model we have targeted the expression of recombinant human parathyroid hormone (hPTH) to the mammary gland yielding hPTH as a secretory, soluble peptide in milk. A 2.5 kb upstream regulatory sequence of the murine whey acidic protein (WAP) directed the expression of the hPTH cD