✦ LIBER ✦

Paraquat induced activation of transcription factor AP-1 and apoptosis in PC12 cells

✍ Scribed by X. Li; A. Y. Sun

Publisher: Springer
Year: 1999
Tongue: English
Weight: 663 KB
Volume: 106
Category: Article
ISSN: 1435-1463
DOI: 10.1007/s007020050137

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Presenilin-1 mutation alters NGF-induced

Presenilin-1 mutation alters NGF-induced neurite outgrowth, calcium homeostasis, and transcription factor (AP-1) activation in PC12 cells

✍ Katsutoshi Furukawa; Qing Guo; Gerard D. Schellenberg; Mark P. Mattson 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 126 KB

Mutations in the presenilin-1 (PS-1) gene are responsible for many cases of autosomal dominant earlyonset inherited Alzheimer's disease (AD). PS-1 is expressed in neurons where it is localized primarily to the endoplasmic reticulum (ER); the normal function of PS-1 and its pathogenic mechanism in AD

Cobalt chloride induces PC12 cells apopt

Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation

✍ Weiguo Zou; Mingda Yan; Weijing Xu; Hairong Huo; Lanying Sun; Zhongcheng Zheng; 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 199 KB

Reactive oxygen species (ROS) are supposed to play an important role in hypoxia-and ischemia/reperfusionmediated neuronal injury with the characteristics of apoptosis. There are many reports showing that cobalt chloride (CoCl 2 ) could mimic the hypoxic responses in some aspects including production

Inhibition of AP-1 transcription activat

Inhibition of AP-1 transcription activator induces myc-dependent apoptosis in HL60 cells

✍ Seyeon Park; Eun-Ryeong Hahm; Dug-Keun Lee; Chul-Hak Yang 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 555 KB

## Abstract Transcriptional activation of AP‐1 is intricately involved in cell proliferation and transformation. The natural product, nordihydroguaiaretic acid (NDGA) shows an inhibitory effect on the binding of jun/AP‐1 protein to the AP‐1 site in 12‐__O__‐tetradecanoylphorbol‐13‐acetate (TPA)‐sti

Constitutive activation of transcription

Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin

✍ Bhupesh K. Prusty; Bhudev C. Das 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 235 KB

Nerve growth factor inhibits apoptosis i

Nerve growth factor inhibits apoptosis induced by tumor necrosis factor in PC12 cells

✍ Ronit Haviv; Reuven Stein 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB 👁 2 views

Tumor necrosis factor-␣ (TNF␣) may play a role in at least some of the neuronal death that occurs following brain insults or in neurodegenerative diseases. It is therefore important to characterize the mechanism underlying apoptosis induced by TNF␣ in neuronal cells and to identify factors capable o

Inhibition of nuclear factor kappa B (NF

Inhibition of nuclear factor kappa B (NFκB) activity induces nerve growth factor-resistant apoptosis in PC12 cells

✍ Giulio Taglialatela; Robert Robinson; J. Regino Perez-Polo 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 118 KB 👁 1 views

The mechanism(s) underlying nerve growth factor (NGF)-mediated rescue of neurons from apoptosis is poorly understood, although it is well established that the high-affinity NGF receptor (TrkA) plays a pivotal role in mediating NGF effects. The report that the low-affinity NGF receptor (p75 NGFR ) ca