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Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5Y cells

✍ Scribed by Wonsuk Yang; Evelyn Tiffany-Castiglioni; Hyun Chul Koh; Il-Hong Son

Book ID
118735073
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
690 KB
Volume
191
Category
Article
ISSN
0378-4274

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## Abstract Neuroblastoma is the most common extracranial solid tumor in children causing death at pre‐school age, as no cure has yet been developed. We investigated the proteolytic mechanisms for apoptosis in human malignant (N‐type) neuroblastoma SH‐SY5Y cells following exposure to flavonoids suc