Parameters influencing theoretical determination of RM-values of naphthalene derivatives in thin-layer chromatography by using binary mobile phase

✍ Scribed by Różyło, J. K. ;Malinowska, I. ;Gross, J.

• Publisher: John Wiley and Sons
• Year: 1980
• Tongue: English
• Weight: 413 KB
• Volume: 3
• Category: Article
• ISSN: 0935-6304
• DOI: 10.1002/jhrc.1240030205

✦ Synopsis

The purpose of the studies being carried out is to find some regularities of a general character which determine the relationship between the structures of the chromatographed substances and the composition of the mobile phase, i.e., between the log of the partition coefficient of the sample (A,), the K1-values which characterize the adsorption equilibrium of component "1" in a given chromatographic system, the structures of the mobile phase components and the structures of the substances being chromatographed. This paper deals with the relationship between the A, and K1 parameters and the structure of naphthalene and a number of its derivatives. It has been shown that there is a close relationship between the kind, size, frequency and site of the substituent on the one hand and the A, and K1 values on the other. In order to eliminate the possibility of unwanted side effects, the investigations were carried exclusively using non-active binary mobile phases of the type N + N or N + /B/. From these investigations, a comparison between the parameter A, and the surface of adsorbed molecules (A,) was also possible.