Paramagnetic tagging for protein structure and dynamics analysis

✍ Scribed by Peter H.J. Keizers; Marcellus Ubbink

• Publisher: Elsevier Science
• Year: 2011
• Tongue: English
• Weight: 783 KB
• Volume: 58
• Category: Article
• ISSN: 0079-6565
• DOI: 10.1016/j.pnmrs.2010.08.001

✦ Synopsis

Molecules containing unpaired electrons affect the magnetic properties of nuclei in their vicinity, which is observable in Nuclear Magnetic Resonance (NMR) spectra. As these effects are strongly distance dependent, the use of unpaired electrons can facilitate NMR structure determinations of (large) molecules and the complexes they form.