Paralytic poliomyelitis in a child with agammaglobulinemia

✍ Scribed by W. Abo; S. Chiba; T. Yamanaka; T. Nakao; M. Hara; I. Tagaya

• Book ID: 104776316
• Publisher: Springer
• Year: 1979
• Tongue: English
• Weight: 324 KB
• Volume: 132
• Category: Article
• ISSN: 0340-6997
• DOI: 10.1007/bf00443199

✦ Synopsis

This paper gives the clinical, immunological and virological data on a patient with agammaglobulinemia who developed paralytic poliomyelitis. The patient was a 3 year-old boy who had a typical B-cell defect without a T-cell defect. He had profound hypogammaglobulinemia and defective plasma cells and had repeated pyogenic infections which were controlled by gammaglobulin replacement therapy. At 3 years of age, he was admitted to our hospital with suspected meningitis. He had fewer, tremor and neck stiffness for 3 days and subsequently developed paralysis in his left arm and right leg. There was lymphocytosis in the cerebrospinal fluid. A non vaccine-like strain of poliovirus type 2 was isolated from the stool.