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Parallel synthesis of novel antitumor agents: 1,2,3-triazoles bearing biologically active sulfonamide moiety and their 3D-QSAR

โœ Scribed by Lili Ou; Shuang Han; Wenbo Ding; Ping Jia; Bo Yang; Jose L. Medina-Franco; Marc A. Giulianotti; Jian-Zhong Chen; Yongping Yu


Book ID
106468456
Publisher
Springer
Year
2011
Tongue
English
Weight
940 KB
Volume
15
Category
Article
ISSN
1381-1991

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Synthesis of novel pyrrole and pyrrolo[2
โœ Mostafa M. Ghorab; Fatma A. Ragab; Helmy I. Heiba; Hanan A. Youssef; Marwa G. El ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 458 KB

a b s t r a c t Pyrroles and pyrrolo [2,3-d]pyrimidines were reported to act as potent anticancer agents, in this work, a series of novel 2-substituted-3-cyano-4-phenyl-pyrrole 5, 6, 11-18, and 5-phenyl-pyrrolo[2,3-d]pyrimidine derivatives 7-10, 19-24 bearing either sulfathiazole or sulfapyridine we