Parallel synthesis and automated data analysis: a versatile decision tool

✍ Scribed by Diggelmann, Martin; Gassmann, Ernst; Stämpfli, Andreas

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 128 KB
• Volume: 55
• Category: Article
• ISSN: 1526-498X
• DOI: 10.1002/(sici)1096-9063(199903)55:3<374::aid-ps914>3.0.co;2-5

✦ Synopsis

added to the culture.5 These results suggest that the antibiotic modiücation is not necessarily a primary self-defence mechanism for all the t-type trichothecene producers, as we have previously discussed.1The type A trichothecene producer would have other defence options dispensable with 3-Oacetylation. These possible options might include modiücation or replacement of the drug target ribosome,6 efficient efflux of the antibiotic by the membrane transporter,7 and restriction of the membrane permeability against substances in the medium,8 which might be substantially defective in the type B producer.