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Parallel Synthesis and anti-Malarial Activity of a Sulfonamide Library.

✍ Scribed by A. Ryckebusch; R. Deprez-Poulain; M.-A. Debreu-Fontaine; R. Vandaele; E. Mouray; P. Grellier; C. Sergheraert


Publisher
John Wiley and Sons
Year
2003
Weight
73 KB
Volume
34
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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A Parallel Synthesis Scheme for Generati
✍ Heike Strobel; Laurence DuguΓ©; Philippe MarliΓ¨re; Sylvie Pochet πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 438 KB πŸ‘ 2 views

We report a combinatorial approach aimed at producing in a single step a large family of nucleoside triphosphate derivatives that could be tested for their ability to be substrates for DNA polymerases. We propose as a unique triphosphate building block a nucleotide with a hydrazine function anchored