Thermal unfolding of small proteins with
โ
Stefan Knapp; Pekka T. Mattson; Petya Christova; Kurt D. Berndt; Andrej Karshiko
๐
Article
๐
1998
๐
John Wiley and Sons
๐
English
โ 344 KB
The thermal unfolding of three SH3 domains of the Tec family of tyrosine kinases was studied by differential scanning calorimetry and CD spectroscopy. The unfolding transition of the three protein domains in the acidic pH region can be described as a reversible two-state process. For all three SH3 d