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Parallel chemistry investigations of ortho-directed hydrogen isotope exchange between substituted aromatics and isotopic water: novel catalysis by cyclooctadienyliridium(I)pentan-1,3-dionates

✍ Scribed by Lee P Kingston; William J.S Lockley; Andrew N Mather; Edward Spink; Stewart P Thompson; David J Wilkinson


Book ID
104210107
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
101 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis


Novel iridium-based catalysts which promote ortho-directed hydrogen isotope exchange between substituted aromatics and isotopic water have been identified via a combination of screening and subsequent ligand optimisation. The catalysts are more active, operate at lower temperature and are applicable to a wider variety of substrates than previously known systems.