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Parallel changes in red blood cell and renal Na−K-ATPase activity in adrenal and electrolyte disorders in the rat

✍ Scribed by H. Wald; P. Scherzer; M. M. Popovtzer

Publisher
Springer
Year
1985
Tongue
English
Weight
585 KB
Volume
404
Category
Article
ISSN
0031-6768

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✍ Philip B. Miner Jr.; Michael Sneller; Synda S. Crawford 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 887 KB

We studied changes in hepatic membrane (Na+,K+)ATPase activity and membrane lipids induced by canrenoate, the water-soluble congener of canrenone, the active metabolite of spironolactone. (Na+,K+)ATPase activity was decreased after canrenoate in a dose- and time-dependent manner. Decreased activity