Parallel and Automated Formation of Lipid Bilayers on Microstructured Chips for Ion Channel and Nanopore Recordings
โ Scribed by Baaken, Gerhard; Kreir, Mohamed; Seifert, Astrid; Beckler, Matthias; Del Rio-Martinez, Juan M.; Hoffmann, Marcel; Petersen, Soenke; Behrends, Jan C.; Fertig, Niels
- Book ID
- 122120757
- Publisher
- Biophysical Society
- Year
- 2013
- Tongue
- English
- Weight
- 59 KB
- Volume
- 104
- Category
- Article
- ISSN
- 0006-3495
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๐ SIMILAR VOLUMES
Purpose: Development of an apparatus for simultaneous measurement of electrical and spectroscopic parameters of single ion-channels.
To quantify the ion-permeation ability of the recombinant โ1-4/1 channel activated by agonists, the magnitude of agonist-induced integrated single-channel currents for the โ2-4/1 N-methyl-D-aspartate (NMDA) channels in bilayer lipid membranes (BLMs) was evaluated electrochemically based on the singl