✦ LIBER ✦

Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease

✍ Scribed by Thomas W. Mitchell; Elliott J. Mufson; Julie A. Schneider; Elizabeth J. Cochran; Jonathan Nissanov; Li-Ying Han; Julia L. Bienias; Virginia M.-Y. Lee; John Q. Trojanowski; David A. Bennett; Steven E. Arnold

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 394 KB
Volume: 51
Category: Article
ISSN: 0364-5134
DOI: 10.1002/ana.10086

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mild cognitive impairment: Aging to Alzh

Mild cognitive impairment: Aging to Alzheimer's disease

✍ Howard Chertkow 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 40 KB 👁 2 views

Magnetization transfer imaging in normal

Magnetization transfer imaging in normal aging, mild cognitive impairment, and Alzheimer's disease

✍ Wiesje M. Van Der Flier; Dominique M. J. Van Den Heuvel; Annelies W. E. Weverlin 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 82 KB 👁 2 views

Limbic hypometabolism in Alzheimer's dis

Limbic hypometabolism in Alzheimer's disease and mild cognitive impairment

✍ Peter J. Nestor; Tim D. Fryer; Peter Smielewski; John R. Hodges 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB 👁 2 views

The neural basis of the amnesia characterizing early Alzheimer's disease (AD) remains uncertain. Postmortem pathological studies have suggested early involvement of the mesial temporal lobe, whereas in vivo metabolic studies have shown hypometabolism of the posterior cingulate cortex. Using a techni

Loss of nucleus basalis neurons containi

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

✍ Elliott J. Mufson; Shuang Y. Ma; Elizabeth J. Cochran; David A. Bennett; Laural 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 323 KB 👁 2 views

Recent studies indicate that there is a marked reduction in trkA-containing nucleus basalis neurons in end-stage Alzheimer's disease (AD). We used unbiased stereological counting procedures to determine whether these changes extend to individuals with mild cognitive impairment (MCI) without dementia

Preservation of nucleus basalis neurons

Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease

✍ Gilmor, Michelle L.; Erickson, Jeffrey D.; Varoqui, H�l�ne; Hersh, Louis B.; Ben 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 473 KB 👁 2 views

Immunocytochemistry for choline acetyltransferase (ChAT) and the vesicular acetylcholine transporter (VAChT) was used to examine the expression of these linked cholinergic markers in human basal forebrain, including cases with early stages of Alzheimer's disease (AD). Previous neurochemical studies

Alternative processing of γ-secretase su

Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and alzheimer's disease: Evidence for γ-secretase dysfunction

✍ Saori Hata; Sayaka Fujishige; Yoichi Araki; Miyako Taniguchi; Katsuya Urakami; E 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 331 KB 👁 1 views

Objective: The most common pathogenesis for familial Alzheimer's disease (FAD) involves misprocessing (or alternative processing) of the amyloid precursor protein (APP) by c-secretase due to mutations of the presenilin 1 (PS1) gene. This misprocessing/alternative processing leads to an increase in t