## Abstract The epidermal growth factor receptor (EGFR) tyrosineโkinase inhibitor gefitinib (Iressaยฎ, ZD1839) has shown promising activity preclinically and clinically. Because comparative investigations of drugโresistant sublines with their parental cells are useful approaches to identifying the m
Paradoxical concentration effect of a homodimerizing antibody against a human non-small cell lung cancer cell line
โ Scribed by Heinz Kohler; Ann Jay Bryan
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 626 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0340-7004
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The cytotoxic activity of a new nitrosourea, TCNU, was compared with that of BCNU in five human small cell lung cancer cell lines in vitro. TCNU was found to be equivalent or inferior to BCNU when compared on a microgram to microgram basis. If the potential of in vitro phase II trials for selection
The effects of bombesin on three human small cell lung carcinoma cell (SCLC) lines (NCI-H69, NCI-H128, and NCI-H345) have been examined and compared to the effects of the peptide on the mouse fibroblast cell line Swiss 3T3, and the rat pituitary tumor cell line GH3W5. While all three SCLC lines expr
In an effort to study the mechanism underlying the observed phenotype-specific response of human lung cancer cell lines to a polyamine analogue, N1,N12-bis(ethyl)spermine(BESpm), we have isolated a BESpm resistant cell line from the BESpm-sensitive large cell lung carcinoma line NCI H157. The mutant