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Paradoxic uptake of Gd-EOB-DTPA by hepatocellular carcinoma in mice: Quantitative image analysis

✍ Scribed by Makoto Fujita; Reiko Yamamoto; Masaya Takahashi; Takashi Tsuji; Tsuyoshi Yamanaka; Tomoaki Miyazawa; Bernhard Fritz-Zieroth; Nobuyuki Terada; Chikazumi Kuroda

Book ID
102373127
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
316 KB
Volume
7
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

To determine whether paradoxic uptake of gadoliniumethoxybenzyl‐diethylenetriamine pentaacetic acid (Gd‐EOB‐DTPA) occurs only with highly differentiated hepatocellular carcinomas, quantitative image analysis was performed in 37 mice with 133 hepatocellular carcinomas. The results of lesion/liver signal intensity measurement and relative enhancement calculation indicate that paradoxic positive enhancement occurs independently of cellular differentiation.

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