Paracoccidioidomycosis (South American blastomycosis) successfully treated with terbinafine: first case report

✍ Scribed by J.M. Ollague; A.M. De Zurita; G. Calero

• Book ID: 104459522
• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 463 KB
• Volume: 143
• Category: Article
• ISSN: 0007-0963
• DOI: 10.1046/j.1365-2133.2000.03614.x

✦ Synopsis

We describe a 63-year-old man who presented with painful malodorous lesions in the perianal, perineal and scrotal regions. Following definitive diagnosis of paracoccidioidomycosis, he was treated initially with trimethoprim/sulphamethoxazole, but there was no clinical improvement. He then received terbinafine (Lamisil) 250 mg twice daily for 6 months. There was rapid resolution of all lesions and complete relief of symptoms, without any associated side-effects. The patient remains clinically well and without any evidence of infection 2 years after discontinuation of terbinafine treatment.