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Paracetamol (Acetaminophen): mechanisms of action

✍ Scribed by BRIAN J. ANDERSON


Book ID
109031747
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
141 KB
Volume
18
Category
Article
ISSN
1155-5645

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ROLE OF MACROPHAGES IN ACETAMINOPHEN (PA
✍ GOLDIN, R. D.; RATNAYAKA, I. D.; BREACH, C. S.; BROWN, I. N.; WICKRAMASINGHE, S. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 452 KB πŸ‘ 1 views

Research into the pathogenesis of acetaminophen (paracetamo1)-induced hepatotoxicity has concentrated on the generation of toxic metabolites by the hepatocytes. It has, however, recently been shown that human macrophages cultured with acetaminophen secrete increased quantities of tumour necrosis fac