Paracentric inversion of a human chromosome 7

✍ Scribed by Hachiro Shimba; Kazuo Ohtaki; Kazumi Tanabe; Toshio Sofuni

• Publisher: Springer
• Year: 1976
• Tongue: English
• Weight: 402 KB
• Volume: 31
• Category: Article
• ISSN: 0340-6717
• DOI: 10.1007/bf00270393

✦ Synopsis

In the course of chromosome studies of atomic bomb survivors in Hiroshima using the trypsin-G-banding and Q-banding methods, a 40-year-old male was found to have an abnormal banding pattern in the long arm of a chromosome 7, although no such abnormality was detected by ordinary staining method. Since all other chromosomes apparently had normal banding patterns, the abnormality was determined to be a paracentric inversion of a chromosome 7, which is described as 46, XY, inv (7) (q22q31). This is the first demonstration of a possible paracentric inversion in man.