Multinucleated giant cells (MNGCs) are reported in many thyroid lesions. This study examines whether their quantity and quality can help in the differential diagnosis. All fine-needle aspirations (FNAs) of the thyroid with a ''significant'' number of MNGCs were reviewed from 1995 -1998. There were 2
Papillary tissue fragments as a diagnostic pitfall in fine-needle aspirations of thyroid nodules
โ Scribed by Christine R. Faser; Edith F. Marley; Yolanda C. Oertel
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 386 KB
- Volume
- 16
- Category
- Article
- ISSN
- 8755-1039
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โฆ Synopsis
Fine-needle aspirates of three thyroid nodules displayed hypercellularity and papillary tissue fragments that suggested neoplasms. Neither microfollicles (either empty or with inspissated colloid) nor the characteristic nuclei of papillary carcinoma were evident. Surgical specimens contained adenomatoid nodules with focal papillary hyperplasia. These cases demonstrate that no single cytologic feature should be used independently in the cytologic diagnosis of thyroid lesions. Tumor cellularity and papillary tissue fragments should not be equated with neoplasia per se; all cytomorphologic features should be evaluated.
๐ SIMILAR VOLUMES
The cytologic diagnosis of primary mediastinal lesions is challenging due to the large number of lesions which may arise (i.e., lymphoma, thymoma, germ cell tumor), often with overlapping cytomorphologic features. We present an instructive case of primary mediastinal non-Hodgkin's large-cell lymphom