Paper Electrophoresis in the Study of Mixed Ligand Complexes in Solution. The System Fe(III)– and Cr (III) — Methyl Cysteine — Penicillamine

✍ Scribed by Brij Bhushan Tewari

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 331 KB
• Volume: 10
• Category: Article
• ISSN: 0269-3879
• DOI: 10.1002/(sici)1099-0801(199609)10:5<221::aid-bmc590>3.0.co;2-o

✦ Synopsis

A method involving use of paper electrophoresis is described for the study of equilibria in mixed ligand [methyl cysteine-penicillamine] complex systems in solution. The concentration of the primary ligand methyl cysteine was kept constant, while that of secondary ligand penicillamine was varied. The plots oflog [penicillamine] against mobility were used to obtain information on the formation of mixed complex and to calculate its stability constants. The binary equilibria M(II1)-methyl cysteine have also been studied since this is a pre-requisite for the investigation of mixed complexes. The stability constants of [Fe(III)methyl cysteinepenicillamine] and [Cr(III)-methyl cysteine -penicillamine] complexes were found to be 7.40* 0.13 and 4.80* 0.07 (log K values) for Fe(II1) and Cr(II1) complexes, respectively, at p=O.1 m o m and at a temperature of 35°C.