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Papaverine, drug-induced stereotypy and catalepsy and biogenic amines in the brain of the rat

✍ Scribed by W. Kostowski; Sylwia Gajewska; A. Bidzinski; Miroslawa Hauptman


Book ID
113217121
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
185 KB
Volume
5
Category
Article
ISSN
0091-3057

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Pyrroxan (20 mg/kg, i.p.) , a new potential antianxiety agent, increased brain norepinephrine (NE) turnover in rats, reflecting a possible central e-adrenergic receptor blocking activity, in contrast, chlordiazepoxide (20 mg/kg, i.p.), a widely used antianxiety agent, did not alter the NE turnover.