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Pancytopenia due to hemophagocytic syndrome as the presenting manifestation of babesiosis

✍ Scribed by Pankaj Gupta; Randolph W. Hurley; Peter H. Helseth; Jesse L. Goodman; Dale E. Hammerschmidt

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
516 KB
Volume
50
Category
Article
ISSN
0361-8609

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✦ Synopsis

We present a case of hemophagocytosis during infection with the intraerythrocytic protozoan Babesia microti in a 47-year-old splenectomized renal allograft recipient. After therapy with clindamycin and quinine a relapse responded to atovaquone; durable remission was not achieved until trimethoprim/sulfa was added. We postulate the severity of our patient's syndrome was due to splenectomy and chronic immunosuppression. Babesiosis should be considered when immunocompromised patients develop pancytopenia.

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