Pancreatic tissue and ductal pressures in chronic pancreatitis
β Scribed by R. P. Jalleh; M. Aslam; Professor R. C. N. Williamson
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 325 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0007-1323
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Our experiments were designed to identify initial biochemical and biological changes that occur during pancreatic carcinogenesis. TAKA-1, an immortal hamster pancreatic ductal cell line, was treated in vitro for up to 11 weeks with the pancreatic carcinogen N-nitorosobis(2-oxopropyl)amine (BOP). The
## Abstract ## Background The strongest risk factors for pancreatic adenocarcinoma are tobacco smoking and increasing age. However, only a few smokers or elderly individuals develop the disease and genetic factors are also likely to be important. ## Methods The literature on genetic factors modi