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Pancreatic stellate cells are immunosuppressive modulators in pancreatic ductal adenocarcinoma

✍ Scribed by Feig, Christine; Jones, James O.; Wells, Richard J.B.; Tuveson, David A.; Fearon, Douglas T.

Book ID
122667196
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
49 KB
Volume
12
Category
Article
ISSN
1424-3903

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## Abstract Pancreatic adenocarcinoma is a disease with high mortality for which chronic pancreatitis confers a markedly increased risk. We hypothesize that chromosome instability and genomic damage occur in pre‐neoplastic pancreatic ductal epithelium, and that this damage may be related to oxidati