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Pancreatic carcinoma in a ten-year survivor of acute myeloblastic leukemia

✍ Scribed by McLaughlin, Peter ;Bennetts, Roland W.

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
877 KB
Volume
10
Category
Article
ISSN
0098-1532

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✦ Synopsis

Abstract

Adenocarcinoma of the pancreas developed in a young man who was a 10‐year survivor of acute myeloblastic leukemia (AML). His extensive cytotoxic chemotherapy for AML is reviewed along with a discussion of its possible oncogenic effects. Other case reports of second malignant neoplasms (SMN) following acute leukemia are cited; available data suggest that the overall risk of SMN in AML may be in the range of 6%. While our patient's second malignancy may have been a chance association, his and other cases of pancreatic carcinoma in young survivors of hematologic neoplasia suggest that the cytotoxic treatment may have had a role in the pathogenesis of the pancreatic carcinoma.

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